Immunogenicity of an Extract of Clostridium chauvoei in Guinea Pigs.

Characterization of Clostridium chauvoei strains isolated from an outbreak of blackleg in Iran

Immunization of guinea-pigs and cattle with a reduced dose Clostridium chauvoei vaccine produced in a semi-synthetic medium.

A semi-synthetic culture medium and method are described for the production of a reduced dose Clostridium chauvoei vaccine. The vaccine gave excellent results in guinea-pigs, and 2 injections of 2.0 ml protected cattle against challenge with 2 M.L.D. of a virulent culture for at least 12 months. The suitability of C. chauvoei Strain OP64 as a vaccine strain was confirmed.

Immunizalion of Cattle with Clostridium chauvoei Vaccine

Clostridium chauvoei, an Evolutionary Dead-End Pathogen

Full genome sequences of 20 strains of Clostridium chauvoei, the etiological agent of blackleg of cattle and sheep, isolated from four different continents over a period of 64 years (1951-2015) were determined and analyzed. The study reveals that the genome of the species C. chauvoei is highly homogeneous compared to the closely related species C. perfringens, a widespread pathogen that affects...

Antitussive Effect of Plantago lanceolata in Guinea Pigs

Background: Several therapeutic effects including anti-asthma and dyspnea have been described for Plantago lanceolata. In the present study the antitussive effect of this plant was evaluated. Methods: The antitussive effects of aerosols of two different concentrations of Soxhlet and macerated ethanolic extracts, codeine and saline were tested by counting the number of coughs produced due to aer...